Professional bio

My name is Patrick Wanner, and I am an anesthetist-intensivist and a clinical researcher specializing in perioperative and intensive care medicine. My passions are caring for critically ill patients, researching ways to make acute care safer, and helping younger colleagues discover the beauty of anesthesia, emergency medicine, and critical care.

During my Anesthesiology and Intensive Care Medicine residencies, I had the privilege of training at a multitude of Swiss institutions (Kantonsspital St. Gallen, Kantonsspital Baden, University Hospital Basel), gaining broad experience in critical care, perioperative care, and preclinical and clinical emergency medicine. I have worked as a prehospital emergency physician for Swiss Air-Rescue (REGA) and in the St. Gallen and Basel ambulance services.

I've gained extensive clinical research experience during my training with my mentors, Prof. Miodrag Filipovic (Kantonsspital St. Gallen / University of Basel), Prof. Luzius A. Steiner (University Hospital Basel / University of Basel) and Prof. PJ Devereaux (Population Health Research Institute / McMaster University). I am investigating strategies to improve the care of high-risk surgical patients and the critically ill. Convinced that research and patient care must be much more personalized, I co-founded the Personalising Acute Care Network, a collaborative network aiming to advance the research and adoption of precision acute care medicine. Moreover, I am leading AUTOREGULATE-NONCARDIAC, a multicenter prospective cohort study investigating precision BP monitoring during and following major noncardiac surgery. Finally, as part of my Masters in Health Research Methodology at McMaster University, I am researching using machine learning in the perioperative setting to predict clinical deterioration.

Last but not least, as a tutor in the Faculty of Medicine at the University of Basel, a mentor in the Joint Medical Master Program of the Universities of St. Gallen and Zurich, and an Advanced Trauma Life Support instructor, I am regularly involved in teaching and mentoring activities.

Current & Recent positionS

• Staff Physician in Anesthesiology, University Hospital of Basel, Switzerland

• Staff Physician in Critical Care, University Hospital of Basel, Switzerland

• Research Fellow under the mentorship of Prof. PJ Devereaux at the Population Health Research Institute (PHRI) & Master’s Candidate in Health Research Methodology at McMaster University, Hamilton, Canada

• Research Fellow under the mentorship of Prof. Luzius A. Steiner at the University Hospital of Basel, Switzerland

Interests

CLINICAL

• Management and resuscitation of the critically ill in all clinical contexts (prehospital, ED, ICU, OR)

RESEARCH

• Precision medicine in intensive care and perioperative medicine with a focus on precision hemodynamic management

• Leveraging large datasets, machine learning and AI in acute care medicine

Clinical training

• Swiss FMH Board Certification in Anesthesiology

• Swiss FMH Board Certification in Intensive Care Medicine

• Prehospital Emergency Medicine (Swiss Society of Emergency and Rescue Medicine) [Fähigkeitsausweis Präklinische Notfallmedizin / Notarzt SGNOR]

Research training

• MSc studies in Health Research Methodology, McMaster University (underway)

• Research Fellowship under mentorship of Prof. PJ Devereaux, Population Health Research Institute (underway)

• Advanced Course in Epidemiological Analysis, London School of Hygiene & Tropical Medicine

Teaching & Mentoring

• Tutor for Tutorials of Scientific & Clinical Reasoning, Medical Faculty, University of Basel

• Instructor Advanced Trauma Life Support

• Mentor Joint Medical Master University of St. Gallen / University of Zurich

Academic activity

Research Networks

• The Personalising Acute Care Network

Research projects

• Association of intraoperative blood pressure excursions below cerebral autoregulatory boundaries with organ injury following major noncardiac surgery (AUTOREGULATE-NONCARDIAC) [NCT05336864]

• Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery (The BBB Study) [NCT02533128]

Research Grants

• Kantonsspital St.Gallen Research Commission: The role of cerebral autoregulation monitoring following major noncardiac surgery – a substudy of the AUTOREGULATE-NONCARDIAC study. [Co-Applicant]

• Swiss Society for Anaesthesiology and Perioperative Medicine (SSAPM) Research Grant: Association of intraoperative blood pressure excursions below cerebral autoregulatory boundaries with organ injury following major noncardiac surgery (AUTOREGULATE-NONCARDIAC). [Principal Applicant]

• Canadian Institutes of Health Research: NeuroVISION-2 Study: Neurological Impact of CerebroVascular Events In Noncardiac Surgery Patients. [Co-Applicant]

• Swiss Heart Foundation Research Grant: Biomarkers, Blood Pressure and BIS: Perioperative risk stratification and management optimization of patients at cardiac risk undergoing major noncardiac surgery (The BBB Study). [Principal Applicant]

Research AWARDS

• Best Paper Award 2022 Swiss Society for Anaesthesiology and Perioperative Medicine (SSAPM): Targeting higher intraoperative blood pressures does not reduce adverse cardiovascular events following noncardiac surgery.

Reviewing activity

• Assistant Editor at the European Journal of Anaesthesiology

• Reviewing activity for Journal of Clinical Anesthesia, Nature Scientific Reports, CJC Open

PUBLICATIONS

• Wildhaber PO *, Wanner PM *, et al. Impact of staff education on the burden of hypotension during major noncardiac surgery. Br J Anaesth 2024; 133: 671–4.

• Kowalik K, Silverman M, Oraii A, et al. Landiolol for perioperative atrial tachyarrhythmias in cardiac and thoracic surgery patients: a systematic review and meta-analysis. Br J Anaesth 2024; 133: 222–5.

• Stroda A, Mauermann E, Ionescu D, et al. Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study. Br J Anaesth 2024; 132: 675–84 [Collaborator]

• Roth S, M’Pembele R, Nienhaus J, et al. Association between self-reported functional capacity and general postoperative complications: analysis of predefined outcomes of the MET-REPAIR international cohort study. Br J Anaesth 2024; 132: 811–4 [Collaborator]

• Wanner PM, Vogt AP, Filipovic M, Steiner LA, Personalising Acute Care Network. Intraoperative hypotension and postoperative outcomes: just the tip of the iceberg. Comment on Br J Anaesth 2023; 131: 823–31. Br J Anaesth 2024; 132: 804–5

• Wanner PM, Filipovic M. Intraoperative hypotension: New answers, but the same old questions. J Clin Anesth. 2024. In press.

• Lurati Buse GA, Mauermann E, Ionescu D, et al. Risk assessment for major adverse cardiovascular events after noncardiac surgery using self-reported functional capacity: international prospective cohort study. Br J Anaesth. Jun 2023;130(6):655-665. doi:10.1016/j.bja.2023.02.030 [Collaborator]

• Wanner PM, Wulff DU, Djurdjevic M, Korte W, Schnider TW, Filipovic M. Targeting higher intraoperative blood pressures does not reduce adverse cardiovascular events following noncardiac surgery. J Am Coll Cardiol. 2021;78:1753-1764.

• Wanner PM, Filipovic M. The Right Ventricle—You May Forget it, but It Will Not Forget You. J. Clin. Med. 2020, 9, 432.

• Kindler M, Wanner PM, Filipovic M. Cardiac risk in non-cardiac surgery: A review, Trends in Anaesthesia and Critical Care. 2018, https://doi.org/10.1016/j.tacc.2018.04.013.

• Yurttas T, Wanner PM, Filipovic M. Perioperative management of antithrombotic therapies. Curr Opin Anaesthesiol 2017.

• Bettex DA, Wanner PM, Bosshart M, et al. Role of sevoflurane in organ protection during cardiac surgery in children: a randomized controlled trial. Interactive CardioVascular and Thoracic Surgery Oxford University Press; 2014;:ivu381

Book chapters

• Wanner PM, Meyfroidt G, Steiner LA. Sedation & Analgesia. In: Oxford Textbook of Neurocritical Care, 2ed, Oxford University Press. In press.

• Wanner PM, Yurttas T, Filipovic M. Intraoperative Management and Its Influence on Postoperative Biomarker Release. In: Biomarkers in Trauma, Injury and Critical Care. Springer. 2022.

• Yurttas T, Wanner PM, Filipovic M. Therapeutic Strategies in Patients with Postoperative Elevation of Cardiac Biomarkers. In: Biomarkers in Trauma, Injury and Critical Care. Springer. 2022.

• Gomes NV, Wanner PM, Goettel N. Newer brain monitoring techniques. In: Prabhakar, ed: Essentials of Evidence-Based Practice in Neuroanesthesia and Neurocritical Care. Elsevier. 2022.

• Wanner PM, Filipovic M. Der rechte Ventrikel - das Wichtigste für den Intensivmediziner. In: Eckart, Forst, Briegel, eds.: Intensivmedizin. Kompendium und Repetitorium zur interdisziplinären Weiter- und Fortbildung. ecomed Verlagsgesellschaft AG & Co. KG, Landsberg. 2018.

PRESENTATIONS

• Perioperatives hämodynamisches Management [Perioperative hemodynamic management] - Past, Present, Future. 78. St. Galler Anästhesiesymposium 2024, St. Gallen, Switzerland

• Why did blood pressure management not work? And what's next? Korean Society of Cardiothoracic and Vascular Anesthesiologists (KSCTVA) Annual Meeting 2023, Seoul, South Korea

• Intraoperative MAPs of 60 or greater versus 75 or greater, Perioperative Care Congress 2022, Society for Perioperative Research and Care / McMaster University, Canada

• Just The Tip Of The Iceberg - Perioperatives Blutdruckmanagement [Perioperative Blood Pressure Management], 67. St. Galler Anästhesie- und Intensivsymposium 2022, St. Gallen, Switzerland

• Raising Blood Pressure in Major Noncardiac Surgery, Poster & Free Communication Presentation, Swiss Society for Anaesthesiology & Resuscitation, Annual Meeting 2019, Interlaken, Switzerland

• Role of Volatile Anesthetics in Organ Protection during Cardiac Surgery in Children, Poster presentation, Society of Cardiovascular Anesthesiologists, 35th Annual Meeting 2013, Miami USA

INTERVIEWS

• Intraoperative Hypotension: Marker or Mediator of Disease? Medscape, October 25 2021

For more information, please contact me by email using the form on the contact page.